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Salton Sea aerosol exposure in mice induces a pulmonary response distinct from allergic inflammation
authors:
Trevor A. Biddle, Qi Li, Mia R. Maltz, Purvi N. Tandel, Rajrupa Chakraborty, Keziyah Yisrael, Ryan Drover, David R. Cocker III, David D. Lo
publication:
Science of the Total Environment
Year:
2021
month:
10 - October
description:
In communities surrounding the Salton Sea, high rates of asthma are associated with high aerosol dust levels. However, the Salton Sea itself may play an additional role in pulmonary health. Therefore, to investigate a potential role of the Salton Sea on pulmonary health, we exposed mice to aerosolized Salton Sea water for 7 days and assessed tissue responses, including cellular infiltration and gene expression changes.
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